At 22, Cole Siefer Built a Functional Medicine Clinic Generating $650K Per Month
After a near-fatal mountain bike accident and a traumatic brain injury, the Maine entrepreneur dropped out of college, built a top-5% podcast, and opened a clinic that now serves 200+ new patients monthly
SOUTH PORTLAND, Maine (June 2026) — Cole Siefer is 22 years old. He runs Med Matrix, a functional medicine clinic in South Portland, Maine, that generates $650,000 per month in revenue, employs 7 providers, and has treated more than 3,000 patients since opening in July 2023.
He doesn’t have a medical degree. He has a mountain bike accident, a traumatic brain injury, and a firsthand understanding of what happens when the healthcare system tells you you’re fine and you know you’re not.
The Accident That Started Everything
At 18, Siefer was in a near-fatal mountain bike accident. He was diagnosed with a traumatic brain injury and autoimmune thyroid issues. Conventional doctors said he was fine. His labs looked “normal.” His symptoms said otherwise.
A functional medicine doctor eventually ran the right tests, found the problems, and helped him recover. That experience changed the direction of his life.
Siefer dropped out of college. He built a podcast focused on health and wellness that reached the top 5% globally and accumulated millions of views. Through that work, he connected with a provider who shared his frustration with the conventional model.
From Zero to $650K Per Month
In July 2023, Siefer opened Med Matrix with a $200,000 loan from his mother and a cosigned $1,000,000 commercial lease. His mom, Carrie Siefer, joined him as the clinic’s Aesthetics Director.
The first year was brutal. Siefer hired agencies, ran his own ads, attended networking events. None of it filled the schedule the way he needed.
“Nothing worked for a long time,” Siefer said. “I was in the trenches every single day. Then something clicked.”
Revenue climbed from $50,000 per month to $650,000 per month over roughly 15 months. The clinic now brings in over 200 new patients each month and holds a 4.9-star rating across 150+ Google reviews.
A Model Built on Time, Not Volume
Med Matrix operates outside of insurance. Every new patient receives a blood panel covering 80+ biomarkers, a full body composition scan, and a 60-minute consultation with their provider. Providers review labs, health history, and symptom questionnaires before the appointment even begins.
“The system most people are used to gives their doctor seven minutes and expects them to figure everything out,” Siefer said. “We give our providers an hour with each patient, plus the prep time to actually review everything beforehand. That’s where the real work happens.”
The clinic’s team of 7 providers covers functional medicine, hormone optimization, peptide therapy, weight management, and med spa services.
Why It Works
Siefer credits the clinic’s growth to two things: outcomes and word of mouth.
“We don’t run the kind of ads where we promise people the moon,” he said. “People come in, they get better, and they tell other people. That’s how we went from empty to 200+ new patients a month.”
The 4.9-star average across 150+ reviews supports that claim. Most reviews reference the same themes: thorough testing, longer appointments, providers who listen, and real results.
What’s Next
Siefer plans to continue expanding the provider team and the clinic’s service lines through 2026. He’s also investing in the clinic’s content platform, including a podcast and blog that cover hormone health, gut function, sleep, nutrition, and autoimmune conditions.
“I’m 22,” he said. “I’ve got time. And I’m not done.”
About Med Matrix
Med Matrix (medmatrixusa.com) is a functional medicine clinic in South Portland, Maine, founded in 2023 by Cole Siefer. The clinic specializes in root-cause healthcare, hormone therapy, advanced lab testing, and personalized treatment plans. With 7 providers and more than 3,000 patients served, Med Matrix has become one of New England’s fastest-growing functional medicine practices.
Media Contact:
Med Matrix South Portland, Maine
